Course: Clinical biochemistry II.

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Course title Clinical biochemistry II.
Course code KAZ/KBI2N
Organizational form of instruction Lecture + Tutorial
Level of course not specified
Year of study not specified
Semester Summer
Number of ECTS credits 5
Language of instruction Czech
Status of course unspecified
Form of instruction Face-to-face
Work placements This is not an internship
Recommended optional programme components None
  • Racek Jaroslav, Prof. MUDr. DrSc.
  • Brož Pavel, MUDr.
  • Drechslerová Taťána, RNDr.
  • Florová Blanka, Mgr.
  • Cibulka Roman, MUDr. Ph.D., MBA
Course content
The basis of the lessons are the lectures. The most important topics will be practiced during the laboratory practicals. Lectures: 1.Laboratory investigation in diabetes mellitus. Diagnostics of diabetes, determination of glucose, glycated hemoglobin, microalbuminuria. Diabetic complications. Diabetes mellitus and pregnancy, other causes of hypo-and hypeglycaemia. 2.Laboratory investigation in hepatic disorder. Differential diagnostics using hyperbilirubinemia. 3.Laboratory markers of tumor. 4.Clinical - biochemical investigation of gastrointestinal tract. Parenteral and enteral nutrition from an aspect of clinical biochemistry. Investigation and observation of nutrition. Malnutrition. Obesity. 5.Laboratory investigation in pregnancy. Adaptation response of organism to pregnancy, changes of physiological limits of laboratory tests in pregnancy. Diagnostic application of laboratory investigation in pregnancy. Specificity of laboratory investigation in childhood and in elderly people. 6.Investigation of cerebrospinal fluid. 7.Hormones. General knowledge of metabolism and determination of hormones. Hormones of hypothalamus, hypophysis, hormones of thyreodid gland, hormones of adrenal glands, sex hormones, tissue hormones. 8.Trace elements. Ferrum (Fe), Copper (Cu), zinc (Zn), selenium (Se) and other trace minerals. Vitamins. 9.-11. Current trends in clinical biochemistry. Automatization and integration of laboratory process, laboratory consolidation, centralization and POCT, term "evidence-based medicine", personalized medicine. Certification and accreditation of laboratories, proper laboratory work. Practicals: 1.-4. Laboratory investigation in kidney disease, function examination including calculations. 5.-8. Hereditary metabolic disorders. 9.-11. Function tests in clinical biochemistry.

Learning activities and teaching methods
Laboratory work, Lecture
  • Contact hours - 77 hours per semester
  • Preparation for laboratory testing; outcome analysis (1-8) - 8 hours per semester
  • Preparation for comprehensive test (10-40) - 20 hours per semester
  • Preparation for an examination (30-60) - 30 hours per semester
professional knowledge
No particular prerequisites specified.
learning outcomes
A student is able to perform laboratory investigation and to assess results of laboratory investigation.
teaching methods
Laboratory work
assessment methods
Oral exam
Recommended literature
  • Dastych, M., Hrdinek, P. a kol. Klinická biochemie, bakalářský obor Zdravotní laborant. Masarykova Univerzita, Lékařská fakulta, Brno, 2008.
  • Racek, J. et al. Klinická biochemie. Praha, Galén, Karolinum, 2006.
  • Štern, P. a kol. Obecná a klinická biochemie pro bakalářské obory studia - CD ROM. Karolinum, Praha, 2005.

Study plans that include the course
Faculty Study plan (Version) Branch of study Category Recommended year of study Recommended semester